Table 3.
Top ten biological processes associated with genes proximal to genome-wide DMRs (for full listing see Supplementary Information 3)
| Biological process | Fold enrichment | Raw P value | FDR |
|---|---|---|---|
| Positive regulation of lymphocyte activation (GO:0051251) | 0.06 | 7.40E−17 | 1.33E−13 |
| B cell receptor signaling pathway (GO:0050853) | 0.13 | 1.70E−14 | 1.53E−11 |
| Phagocytosis (GO:0006909) | 0.29 | 5.61E−10 | 3.36E−07 |
| Regulation of lymphocyte activation (GO:0051249) | 0.29 | 8.67E−10 | 3.89E−07 |
| Regulation of leukocyte activation (GO:0002694) | 0.31 | 2.71E−09 | 9.72E−07 |
| Antigen receptor-mediated signaling pathway (GO:0050851) | 0.34 | 6.22E−09 | 1.86E−06 |
| Regulation of cell activation (GO:0050865) | 0.32 | 7.86E−09 | 2.02E−06 |
| Immune response (GO:0006955) | 0.58 | 1.71E−08 | 3.84E−06 |
| B cell activation (GO:0042113) | 0.35 | 3.01E−08 | 6.00E−06 |
| Defense response to bacterium (GO:0042742) | 0.38 | 8.60E−08 | 1.54E−05 |