Table 2.

Mean VTI, LFD metrics, and TRBF in SCR and NC groups

	SCR (15 eyes)	NC (26 eyes)	β	P-value
VTI	0.61 ± 0.36	0.42 ± 0.11	0.28	0.02*
VD	0.51 ± 0.06	0.50 ± 0.04	0.01	0.47
SSV	0.32 ± 0.02	0.35 ± 0.01	−0.03	0.002*
SLV	0.17 ± 0.05	0.15 ± 0.03	0.02	0.31
TRBF (μL/min)	70.42 ± 32.30	45.85 ± 11.97	26.27	0.03*

Data are presented as mean ± standard deviation; β = effect estimates were derived by mixed model analysis, adjusted for eye and mean arterial pressure. Effect estimates are reported with NC as reference. Statistically significant difference is indicated by an asterisk (*)

SCR   sickle cell retinopathy, NC  normal control, VTI  vessel tortuosity index, VD  vessel density, SSV   spacing between small vessels, SLV  spacing between large vessels, TRBF  total retinal blood flow