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. 2020 Apr 4;49(4):618–629. doi: 10.1007/s11239-020-02090-y

Table 3.

Prevalence of thrombophilic defects in the general population and patients with VTE

Prevalence in the general population (%) Prevalence in VTE cohort (%) Annual VTE Risk (%/y)
Antithrombin deficiency 0.02 0.5 1.1
Protein C deficiency 0.15 6 0.7
Protein S deficiency 0.1 2 0.3
FV Leiden heterozygous 5 16 0.5
FV Leiden homozygous 0.004 0.01 1.3
FII G20210A heterozygous 2 7 0.4
FII G20210A homozygous 0.1 2 1.1
FV Leiden/FII heterozygous 0.1 3 0.5