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. 2020 Apr 24;40(4):BSR20200554. doi: 10.1042/BSR20200554

Table 3. Stratified analyses between rs11588607/rs4454537 polymorphisms and the risk of osteoporosis.

Variable Case/Control Heterozygous Homozygous Recessive Dominant
CC CT TT CT vs. CC TT vs. CC TT vs. CT+CC TT+CT vs. CC
rs11588607
Age
  <60 years 55/65 49/60 13/10 0.94 (0.55,1.60); 0.815 1.40 (0.57,3.44); 0.470 1.44 (0.61,3.42); 0.412 1.01 (0.61,1.67); 0.976
  ≥60 years 90/104 84/83 19/17 1.18 (0.78,1.78); 0.428 1.37 (0.67,2.78); 0.390 1.27 (0.64,2.51); 0.500 1.21 (0.82,1.79); 0.337
BMI
  <25 kg/m2 96/117 87/98 24/20 1.08 (0.73,1.61); 0.696 1.46 (0.76,2.81); 0.253 1.41 (0.75,2.64); 0.282 1.15 (0.79,1.67); 0.474
  ≥25 kg/m2 49/52 46/45 8/7 1.09 (0.62,1.91); 0.778 1.21 (0.41,3.60); 0.728 1.17 (0.41,3.34); 0.774 1.10 (0.64,1.90); 0.727
Smoking
  No 131/155 124/137 30/24 1.07 (0.77,1.50); 0.690 1.48 (0.82,2.65); 0.190 1.43 (0.82,2.51); 0.212 1.13 (0.82,1.56); 0.450
  Yes 14/14 9/6 2/3 1.50 (0.42,5.35); 0.532 0.67 (0.10,4.62); 0.682 0.58 (0.09,3.83); 0.571 1.22 (0.39,3.86); 0.733
Drinking
  No 117/143 105/115 27/23 1.12 (0.78,1.60); 0.551 1.44 (0.78,2.63); 0.244 1.36 (0.76,2.45); 0.298 1.17 (0.83,1.65); 0.370
  Yes 28/26 28/28 5/4 0.93 (0.44,1.96); 0.846 1.16 (0.28,4.80); 0.837 1.21 (0.31,4.73); 0.789 0.96 (0.47,1.97); 0.906
Variable Case/Control Heterozygous Homozygous Recessive Dominant
TT TC CC TC vs. TT CC vs. TT CC vs. TC+TT CC+TC vs. TT
rs4454537
Age
  <60 years 55/77 50/51 10/7 1.39 (0.82,2.36); 0.221 2.13 (0.73,6.22); 0.165 1.85 (0.65,5.27); 0.247 1.48 (0.89,2.46); 0.132
  ≥60 years 99/115 74/76 20/13 1.10 (0.73,1.66); 0.657 1.72 (0.83,3.58); 0.148 1.65 (0.81,3.37); 0.168 1.19 (0.81,1.76); 0.384
BMI
  <25 kg/m2 99/135 89/86 19/14 1.41 (0.95,2.09); 0.087 1.85 (0.89,3.87); 0.102 1.60 (0.78,3.27); 0.202 1.47 (1.01,2.15); 0.044
  ≥25 kg/m2 57/57 35/41 11/6 0.85 (0.48,1.53); 0.594 1.83 (0.64,5.29); 0.263 1.95 (0.69,5.50); 0.205 0.98 (0.57,1.69); 0.939
Smoking
  No 145/182 113/115 27/19 1.23 (0.88,1.73); 0.226 1.78 (0.95,3.34); 0.070 1.64 (0.89,3.01); 0.114 1.31 (0.95,1.81); 0.099
  Yes 11/10 11/12 3/1 0.83 (0.26,2.72); 0.763 2.73 (0.24,30.66); 0.416 3.00 (0.29,31.11); 0.357 0.98 (0.31,3.07); 0.971
Drinking
  No 129/160 100/108 20/13 1.15 (0.80,1.64); 0.448 1.91 (0.91,3.98); 0.085 1.80 (0.88,3.70); 0.110 1.23 (0.87,1.73); 0.237
  Yes 27/32 24/19 10/7 1.50 (0.68,3.30); 0.317 1.69 (0.57,5.05); 0.345 1.43 (0.50,4.05); 0.502 1.55 (0.75,3.19); 0.235

BMI, body mass index

Bold values are statistically significant (P<0.05).