Table 4. The clinical and biochemical characteristics of GREM2 rs4454537 polymorphism among two groups.
| Variables | TT | CT | CC | P |
|---|---|---|---|---|
| Osteoporosis | ||||
| Age (years) | 63.09 ± 8.55 | 62.18 ± 8.07 | 63.57 ± 9.30 | 0.576 |
| BMI (kg/m2) | 24.54 ± 1.44 | 24.20 ± 1.35 | 24.50 ± 1.78 | 0.127 |
| Serum calcium (mg/dL) | 9.32 ± 0.66 | 9.30 ± 0.65 | 9.29 ± 0.56 | 0.954 |
| Serum phosphorus (mg/dL) | 4.73 ± 3.42 | 4.44 ± 1.96 | 4.06 ± 1.51 | 0.407 |
| BMD L2-L4 (g/cm2) | 0.74 ± 0.067 | 0.72 ± 0.063 | 0.72 ± 0.055 | 0.012 |
| T-score | -3.14 ± 0.37 | -3.25 ± 0.39 | -3.17 ± 0.43 | 0.051 |
| Control | ||||
| Age (years) | 62.81 ± 8.58 | 62.42 ± 7.86 | 64.90 ± 8.33 | 0.462 |
| BMI (kg/m2) | 24.22 ± 1.51 | 24.29 ± 1.54 | 24.42 ± 1.57 | 0.806 |
| Serum calcium (mg/dL) | 9.58 ± 0.56 | 9.53 ± 0.59 | 9.41 ± 0.44 | 0.383 |
| Serum phosphorus (mg/dL) | 4.56 ± 3.29 | 3.99 ± 1.98 | 4.18 ± 5.05 | 0.254 |
| BMD L2-L4 (g/cm2) | 1.01 ± 0.055 | 1.01 ± 0.055 | 1.00 ± 0.069 | 0.566 |
| T-score | 0.10 ± 0.01 | 0.10 ± 0.10 | 0.09 ± 0.01 | 0.688 |
Bold values are statistically significant (P<0.05).