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. 2019 Jul 26;42(12):zsz173. doi: 10.1093/sleep/zsz173

Figure 5.

Figure 5.

Elongated circadian period of sleep in DS mice under constant conditions. (A) Top panel: representative double-plotted actogram of total sleep bouts from a WT mouse. Shaded bars indicate times of lights off. Bottom panel: Sokolov-Bushell periodogram calculated for mouse above revealed an endogenous period of 23.6 hours. Red line indicates threshold of significance for the measured period. WT mice had a mean period of 23.64 hours. (B) Same as (A) for one DS mouse with period of 24 hours. Mean period for DS mice was 23.87 hours. (C) Mean waveform of sleep bouts under constant darkness for WT mice. (D) Same as (C) for DS mice. (E) DS mice have a significantly longer period of total sleep in constant darkness than WT mice (two-tailed Student t-test, p = 0.01, n = 3 WT mice, 5 DS mice).