Figure 2.

Theoretical Risk Reduction Model. This model describes our theoretical patient management model which includes 4 components: 1) Identify patients at increased risk for impaired respiratory muscle (respiratory muscle) performance; 2) measure respiratory muscle performance in patients screened for high risk of impaired respiratory muscle performance using either static maximal inspiratory pressure or the test of incremental respiratory endurance (TIRE); 3) clinical pathways for respiratory muscle training (respiratory muscle training) in patients with impaired respiratory muscle performance, which involve either follow-ups every 4 weeks in clinic, home-based monitoring using telehealth or mobile apps, or patients previously enrolled would initiate an urgent 5-week protocol at the start of an outbreak by receiving a notification on their mobile app; and 4) the downstream benefits would involve reducing the use of intensive care unit and mechanical ventilation resources as a result of COVID-related acute respiratory distress syndrome and improving clinical outcomes.