. 2018 Oct 20;21(9):1274–1278. doi: 10.1093/ntr/nty221

Table 1.

Nicotine, Free Radicals, and Carbonyls in Juul Aerosols and PG:GLY Levels in Juul E-Liquids by Flavor

		Flavors
		Tobacco	Creme brulee	Fruit punch	Mint	30:70	60:40	Citral
E-liquid	PG:GLY	29:71^a	31:69^b	31:69^b	30:70^a	30:70	60:40	60:40
E-liquid	PG:GLY	(n = 3)	(n = 3)	(n = 3)	(n = 3)	30:70	60:40	60:40
Per puff	Nicotine (µg/puff)	156.66 ± 47.65	169.91 ± 14.46	154.41 ± 48.84	188.42 ± 24.69	n/a	n/a	n/a
	Nicotine (µg/puff)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	n/a	n/a	n/a
	Free radicals (pmol/puff)	5.90 ± 1.62^a	6.13 ± 1.12^a	5.47 ± 1.79^a	5.90 ± 0.63^a	7.92 ± 1.09^a,b	9.37 ± 1.16^b	10.87 ± 0.83^b
	Free radicals (pmol/puff)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Formaldehyde (µg/puff)	0.23 ± 0.10^a	0.12 ± 0.06^a	0.26 ± 0.08^a	0.19 ± 0.13^a	0.34 ± 0.04^a	0.31 ± 0.07^a	0.69 ± 0.21^b
	Formaldehyde (µg/puff)	(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Acetone (µg/puff)	0.19 ± 0.08^a	0.17 ± 0.02^a	0.20 ± 0.05^a	0.22 ± 0.06^a	0.32 ± 0.12^a,b	0.57 ± 0.15^b	1.19 ± 0.16^c
	Acetone (µg/puff)	(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Acetaldehyde (µg/puff)	n/d	n/d	n/d	n/d	0.00 ± 0.01^a	0.05 ± 0.05^a	0.13 ± 0.03^b
	Acetaldehyde (µg/puff)	(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Propionaldehyde (µg/puff)	n/d	n/d	n/d	n/d	n/d	0.03 ± 0.03	0.05 ± 0.04
	Propionaldehyde (µg/puff)	(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
Per gram e-liquid consumed	Nicotine (mg/g)	78.33 ± 23.82	63.72 ± 5.42	66.17 ± 20.93	94.21 ± 12.34	n/a	n/a	n/a
	Nicotine (mg/g)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	n/a	n/a	n/a
	Free radicals (nmol/g)	2.95 ± 0.81^a	2.56 ± 0.34^a	2.32 ± 0.18^a	2.95 ± 0.32^a	3.01 ± 0.28^a	4.68 ± 0.58^b	4.78 ± 0.73^b
	Free radicals (nmol/g)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Formaldehyde (µg/g)	72.61 ± 35.88^a	42.88 ± 15.07^a	98.91 ± 34.24^a,b	67.12 ± 41.81^a	103.65 ± 14.84^a,b	97.39 ± 34.18^a,b	197.07 ± 83.48^b
		72.61 ± 35.88^a	42.88 ± 15.07^a	98.91 ± 34.24^a,b	67.12 ± 41.81^a	103.65 ± 14.84^a,b	(n = 3)	(n = 3)
		(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Acetone (µg/g)	59.66 ± 22.45^a	67.76 ± 24.94^a	75.16 ± 6.21^a	80.45 ± 38.25^a	95.23 ± 23.91^a,b	171.56 ± 39.32^b	327.48 ± 37.47^c
	Acetone (µg/g)	(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Acetaldehyde (µg/g)	n/d	n/d	n/d	n/d	0.82 ± 1.44^a	14.92 ± 15.30^a,b	36.70 ± 14.24^b
	Acetaldehyde (µg/g)	(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)
	Propionaldehyde (µg/g)	n/d	n/d	n/d	n/d	n/d	8.07 ± 8.99	14.09 ± 14.22
	Propionaldehyde (µg/g)	(n = 4)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)	(n = 3)

Values are means ± SD. Different letters indicate significant differences (p < .05) between flavors. n/d represents that no quantifiable amounts were observed with our setup.