Table 2.
Inter-telomeric distance (distance between the telomeric end of the short arm and the telomeric end of the long arm) for chromosome 1, and chromosomal territories measured with whole chromosomal painting probes, for two chromosomes involved in none of the subject’s translocations (chromosomes 1 and 17). Expressed here are the ratios between the area of the chromosome and the total area of the sperm nucleus. Chromosomal territories are increased for all subjects for chromosome 1, and for all but S2 for chromosome 17. A Kruskal-Wallis one-way ANOVA test was used for statistical analysis, and results with p < 0.05 were considered to be statistically significant
| Inter-telomeric distance (chromosome 1) in nm | Inter-telomeric distance (chr 1), overhead length | Chromosome 1 territory area (over total nucleus area) | Chromosome 17 territory area (over total nucleus area) | |
|---|---|---|---|---|
| C1 | 238 nm | 5% | 13.5% | 5.5% |
| C2 | 164 nm | 3.6% | 13.1% | 5.2% |
| C3 | 129 nm | 2.7% | 8.3% | 4.3% |
| C4 | 270 nm | 5.5 | 7.9% | 2.7% |
| C5 | 133 nm | 2.5% | 8.2% | 2.9% |
| Controls |
187 SEM, 29 nm |
3.9% SEM, 0.6 pp |
10.5% SEM, 0.4 pp |
4.1% SEM, 0.1 pp |
| S1 | 425* (p < 0.05) | 8.9%* (p < 0.05) | 17.5%* (p < 0.00001) | 4.8%* (p < 0.05) |
| S2 | 767* (p < 0.00001) | 16.2%* (p < 0.00001) | 15.7%* (p < 0.00001) | 4.4% |
| S3 | 1150* (p < 0.00001) | 24.4%* (p < 0.00001) | 15.5%* (p < 0.00001) | 8.7%* (p < 0.00001) |
| S4 | 683* (p < 0.001) | 13.7%* (p < 0.001) | 12.2%* (p < 0.0001) | 5.2%* (p < 0.00001) |
| S5 | 533* (p < 0.01) | 10.1%* (p < 0.01) | 10.7* (p < 0.05) | 6%* (p < 0.00001) |
| All subjects |
708* (p < 0.00001) SEM, 50 nm |
14.6%* (p < 0.00001) SEM, 1.08 pp |
14.3%* (p < 0.00001) SEM, 0.3 pp |
5.8%* (p < 0.00001) SEM, 0.2 pp |