Table 2.

Frequently modulated miRNA expression in HBV related liver diseases

Clinical stage	miRNA	Genomic Location	Expression	Refs.
Chronic HBV	miR-122	18q21.3	Up regulation	[67, 68]
	miR- 204	9q21.12	Down regulation	[69]
	Let7c	21q21.1	Up regulation	[68]
	miR-23b	9q22.32	Up regulation	[68]
	miR-150	19 q13.33	Up regulation	[68]
Liver cirrhosis/Fibrosis	miR-29	7q32.3	Down regulation	[70–73]
	miR-133a	18q11.2	Down regulation	[74]
	miR-199	9q34.11	up regulation	[75]
	miR-214 5p	1q24.3	Up regulation	[76]
	miR-221/222	Xp11.3	Up regulation	[77]
Hepatocellular carcinoma	(*) miR-17-92 cluster	13q31.3	Up regulation	[78]
	miR-21	17q23.2	Up regulation	[78]
	miR-96	7q32.2	Up regulation	[79]
	miR-375	2q35	Up regulation	[80]
	miR-92a	5q14.3	Up regulation	[80]
	miR-101-1	1p31.3	Down regulation	[81]
	miR-199b	9q34.11	Down regulation	[81]
	miR-244	Xq28	Up regulateion	[81]
	miR-155	21q21.3	Up regulateion	[82]
	miR-122	18q21.3	Down regulation	[83]
	miR-145	5q32	Down regulation	[84]
	miR-132	17p13.3	Down regulation	[85]
	miR-34a	1p36.22	Down regulation	[58]
	miR-23a	19p13.12	Down regulation	[86]
	miR-148a	7p15.2	Down regulation	[87]
	miR-192	11q13.1	Down regulation	[88]
	miR-125b	11q24.1	Down regulation	[89]
	miR-200	1p36.33	Down regulation	[90]
	miR-602	9q34.3	Up regulation	[91]

(*) miR-17-92 cluster (miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92a-1)