Table 3.
Relation between the levels of expression of H19 and MALAT1 with type-2 diabetes, metabolic syndrome, and biochemical measurements.
| Serum |
Exosomes |
|||||||
|---|---|---|---|---|---|---|---|---|
| H19 |
MALAT1 |
H19 |
MALAT1 |
|||||
| β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | |
| T2D | −0.24 (−1.0, 0.56) | 0.555 | −0.62 (−0.96, −0.27) | < 0.001 | −0.43 (−1.5, 0.68) | 0.444 | −0.70 (−1.25, −0.15) | 0.013 |
| MetS | −0.53 (−1.41, 0.35) | 0.240 | −0.33 (−0.71, 0.06) | 0.099 | −0.34 (−1.48, 0.81) | 0.565 | −0.64 (−1.19, −0.09) | 0.023 |
| WC, cm ≥ 102 male/88 female |
−0.22 (−1.02, 0.58) | 0.591 | 0.01 (−0.35, 0.38) | 0.946 | 0.53 (−0.55, 1.62) | 0.336 | −0.50 (−1.07, 0.06) | 0.080 |
| BP, mmHg ≥135/85 |
−0.26 (−1.19, 0.67) | 0.589 | −0.21 (−0.66, 0.25) | 0.374 | 0.80 (−0.48, 2.08) | 0.223 | −0.25 (−0.98, 0.47) | 0.495 |
| TG, mg/dL ≥ 150 | −0.42 (−1.22, 0.37) | 0.298 | −0.03 (−0.40, 0.33) | 0.855 | −0.42 (−1.54, 0.70) | 0.465 | −0.07 (−0.66, 0.51) | 0.804 |
| HDL-c, mg/dL <40 male/50 female |
0.34 (−0.46, 1.13) | 0.406 | −0.47 (−0.83, −0.12) | 0.009 | −0.49 (−1.62, 0.63) | 0.389 | −0.15 (−0.76, 0.44) | 0.618 |
| HbA1c ≥ 7% | 1.07 (−0.05, 2.19) | 0.060 | −0.14 (−0.45, 0.16) | 0.375 | 0.42 (−1.38, 2.23) | 0.645 | −0.03 (−0.80, 0.74) | 0.945 |
Β, Regression coefficient calculated by generalized linear models adjusted for age; CI, Confidence interval; T2D, Type-2 diabetes; MetS, Metabolic syndrome; WC, Waist circumference; BP, Blood pressure; TG, Triglycerides; HDL-c, High-density lipoprotein cholesterol; HbA1c, Glycosylated hemoglobin.