Table 3.

Cox regression models to predict 1-year post-transplant mortality.

	Reference	Hazard ratio, 95% CI*	Hazard ratio, 95% CI**	Hazard ratio, 95% CI***	Hazard ratio, 95% CI****	Hazard ratio, 95% CI†
ACLF grade 0–2 at LT	ACLF grade 3 at LT	0.74 (0.63–0.88)	0.65 (0.53–0.78)	0.65 (0.54–0.79)	0.67 (0.55–0.81)	0.63 (0.52–0.78)
Age 40–60	Age <40	1.14 (0.92–1.42)	1.13 (0.91–1.42)		1.13 (0.89–1.43)	1.12 (0.88–1.43)
Age >60		1.70 (1.33–2.16)	1.68 (1.31–2.18)		1.74 (1.33–2.27)	1.74 (1.32–2.28)
Age		1.02 (1.01–1.02)		1.01 (1.00–1.02)
MELD-Na score		1.01 (1.01–1.02)	0.97 (0.96–1.00)	0.98 (0.97–1.00)	0.97 (0.98–1.00)	0.97 (0.96–1.01)
ALD	NASH	0.91 (0.78–1.05)
Diabetic	Non-diabetic	1.26 (1.07–1.48)	1.18 (1.00–1.39)	1.18 (1.00–1.39)	1.10 (0.92–1.33)	1.17 (0.98–1.42)
DRI ≥1.7	DRI <1.7	1.24 (1.05–1.46)	1.22 (1.03–1.45)	1.22 (1.03–1.45)	1.18 (0.98–1.42)	1.14 (0.94–1.39)
Time to LT (days)		1.00 (0.99–1.01)
Years 2012–2017	Years 2004–2011	0.88 (0.77–1.02)

^*Univariable analysis.

^**Multivariable analysis.

^***Multivariable analysis, age as continuous variable.

^****Sensitivity analysis after removal of simultaneous liver-kidney transplantation (n = 506).

^†Sensitivity analysis after removal of HCV-infected patients (n = 1,089). ACLF, acute-on-chronic liver failure; ALD, alcohol-related liver disease; DRI, donor risk index; LT, liver transplantation; MELD-Na, model for end-stage liver disease-sodium; NASH, non-alcoholic steatohepatitis.