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ZnO NPs inhibited PGC-1a pathway in hiPSC-CMs. HiPSC-CMs were treated with ZnO NPs at 0, 25, 50, and 100 μM for 6 h. Representative images of the protein expression of PGC-1α, TFAM, and COX IV detected by Western blot (A), and quantitative analysis (B–D). Data were presented as mean ± SE (n = 3). *Compared with control, P < 0.05.
