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editorial

. 2020 Mar 9;69(5):683–687. doi: 10.1007/s00262-020-02543-6

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© The Author(s) 2020

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Fig. 2 — Association between tumor mutational burden (median number of coding somatic mutations per megabase) and immune-related adverse events during Anti-CTLA-4/Anti-PD-1 combination therapy. The straight line represents the linear fit. Circle size and color represent the total number of FAERS cases for each cancer type. Pearson correlation coefficient (r) and the corresponding p value are shown at bottom-right of the figure. The p value means the probability of getting higher r with random ROR values