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. 2020 Apr 25;20:126. doi: 10.1186/s12903-020-01109-3

Table 4.

Quality of available evidence

Quality assessment No of patients Effect Quality
Studies Risk of bias Inconsistency Indirectness Imprecision Other Probiotic Control
Enamel demineralization development
1 Not serious Not serious Not serious Serious1 None 42 43 No difference

⨁⨁⨁◯

Moderate

Gingival inflammation development
3 Not serious Not serious Not serious Seriousa None 81 71 No difference

⨁⨁⨁◯

Moderate

aThe number of patients analyzed was limited