Table 1.
Demographic and baseline characteristics
| Exenatide group (n = 27) | Insulin group (n = 32) | P value | |
|---|---|---|---|
| Sex (male/female) | 19/8 | 14/18 | 0.038 |
| Age (years) | 58.85 ± 12.54 | 58.03 ± 13.32 | 0.657 |
| Weight (kg) | 68.68 ± 11.95 | 66.30 ± 11.42 | 0.438 |
| BMI (kg/m2) | 23.64 ± 2.86 | 24.36 ± 2.52 | 0.313 |
| Diabetes durations (years) | 6.59 ± 5.32 | 7.81 ± 6.02 | 0.417 |
| Systolic pressure (mmHg) | 127.03 ± 16.48 | 125.46 ± 15.04 | 0.704 |
| Diastolic pressure (mmHg) | 80.18 ± 9.65 | 75.15 ± 9.11 | 0.044 |
| Fasting glucose (mmol/L) | 10.38 ± 2.95 | 10.81 ± 2.52 | 0.544 |
| HbA1c (%) | 8.67 ± 1.03 | 8.32 ± 0.96 | 0.195 |
| Total cholesterol (mmol/L) | 4.69 ± 1.40 | 4.62 ± 0.86 | 0.826 |
| Triglyceride (mmol/L) | 2.18 ± 1.50 | 2.10 ± 1.49 | 0.834 |
| Low-density lipoprotein cholesterol (mmol/L) | 2.18 ± 1.50 | 2.10 ± 1.49 | 0.423 |
| High-density lipoprotein cholesterol (mmol/L) | 1.06 ± 0.31 | 1.13 ± 0.24 | 0.335 |
| Uric acid (µmol/L) | 307.51 ± 102.65 | 288.53 ± 80.16 | 0.428 |
| Hypersensitive C reactive protein (mg/L) | 2.93 ± 3.15 | 2.02 ± 1.88 | 0.170 |
| Fibrinogen (g/L) | 2.88 ± 0.65 | 2.92 ± 0.54 | 0.810 |
| 8-OHdG (ng/mL) | 6.60 ± 0.49 | 6.59 ± 0.67 | 0.941 |
| Statins (n) | 4 | 11 | 0.086 |
| Aspirin (n) | 5 | 9 | 0.388 |
| Calcium antagonists (n) | 6 | 9 | 0.604 |
| ARB/ACEI (n) | 9 | 11 | 0.933 |
| Beta blockers (n) | 4 | 2 | 0.278 |
BMI body mass index, HbA1c glycosylated hemoglobin, 8-OHdG 8-hydroxydeoxyguanosine