Table 2.
Demographics and characteristics of patients enrolled in the NPC Registry (N = 472)
| Patient characteristics of overall population (N = 472) |
Patients with age at neurological onset data | ||||
|---|---|---|---|---|---|
| Early-infantile (< 2 years) | Late-infantile (2 to < 6 years) | Juvenile (6 to < 15 years) | Adolescent/adult onset (≥ 15 years) | ||
| Male: female, n (%a) | 245 (51.9): 227 (48.1) | – | – | – | – |
| Age at enrollment | |||||
| n | 470 | – | – | – | – |
| Mean (SD), years | 21.2 (15.0) | – | – | – | – |
| Median (range), years | 19.0 (0.2–71.8) | – | – | – | – |
| Age at onset of neurological symptoms | |||||
| n (%a) | 422 (100.0) | 57 (13.5) | 108 (25.6) | 134 (31.8) | 123 (29.1) |
| Mean (SD), years | 12.3 (11.8) | 0.8 (0.7) | 4.0 (1.2) | 10.1 (2.6) | 27.2 (11.0) |
| Median (range), years | 8.8 (0.0–71.8) | 0.8 (0.0–2.0) | 4.0 (2.0–6.0) | 10.0 (6.0–15.0) | 25.0 (15.0–71.8) |
| Age at diagnosis | |||||
| n (%a) | 292 (100.0) | 37 (12.7) | 84 (28.8) | 87 (29.8) | 84 (28.8) |
| Mean (SD), years | – | 3.3 (4.6) | 8.3 (7.4) | 16.3 (8.6) | 33.5 (12.4) |
| Median (range), years | – | 1.6 (0.1–21.4) | 6.7 (0.1–33.1) | 13.9 (2.9–56.3) | 31.8 (14.4–69.8) |
SD Standard deviation
aPercentage based on patients with data (excluding missing responses)