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. 2020 Apr 26;20:127. doi: 10.1186/s12876-020-01252-9

Table 3.

Medication use by IBS-D severity

N (%) Mild IBS-D (n = 124) Moderate IBS-D (n = 158) Severe IBS-D (n = 193)
Types of medication used over the past 12 monthsa
 Antidiarrhoeal 94 (76) 124 (78) 167 (87)*
 Antispasmodic 71 (57) 99 (63) 112 (58)
 Analgesic 17 (14) 27 (17) 33 (17)
 Codeine-based painkiller 18 (15) 28 (18) 43 (22)
 Antidepressant 14 (11) 25 (16) 38 (20)*
 Other 9 (7) 11 (7) 15 (8)
Current medication useb
 OTC medication only 59 (48) 66 (42) 75 (39)
 Prescription and OTC medication 30 (24) 46 (29) 69 (36)*
 Prescription medication only 35 (28) 46 (29) 49 (25)

*p < 0.05 vs patients with mild IBS-D; p < 0.05 vs patients with moderate IBS-D.

aBased on responses to the question: ‘Which of the following have you taken in the past 12 months for your IBS?’

bBased on responses to the question: ‘Do you take either of the following to help manage your IBS?’

IBS irritable bowel syndrome; IBS-D diarrhoea-predominant irritable bowel syndrome; OTC over-the-counter