Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 15;31(4):244–260. doi: 10.1091/mbc.E19-05-0303

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Arnés et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License.

PMC Copyright notice

FIGURE 7: — PI3K activation increases Aβ42 protein deposits without affecting transcription. (A–D) Representative confocal images of 15-d-old adult heads stained with 6E10 antibody of the indicated genotypes. Note the large increase of amyloid deposits (white) revealed by the 6E10 antibody. Cell nuclei are marked by DAPI (magenta). (E) Western blot of adult heads of the same genotypes and age. Data correspond to three independent Western blots normalized for tubulin content as internal control. Note the significant increase of the 6E10 signal elicited by PI3K activation. One-way ANOVA significance is indicated with **, p < 0.01. (F) RT-qPCR data from the same genotypes and ages. Data represent mean ± SD. Statistical significance was analyzed by Student’s t test. Scale bar is 50 µm.