Table 2.

Linear mixed effect model that predicts the global resting state functional connectivity (rs-fc) signature

rs-fc Signature ∼ Converter+Years to Onset+APOE4+Converter:Years to Onset+Gender+Education+APOE4:Years to Onset+(1|ID)
	β	CI	p
Fixed Effects
(Intercept)	−1.069	(−2.429, 0.292)	0.124
Non-Converter	0.352	(0.079, 0.626)	3.70e-03**
Years to Onset	−0.150	(−0.224, −0.087)	6.21e-05***
APOE ε4+	−0.077	(−0.278, 0.125)	0.469
Gender	−0.076	(−0.444, 0.292)	0.683
Education	0.054	(−0.014, 0.122)	0.120
Non-Converter × Years to Onset	0.090	(0.029, 0.151)	3.66e-03**
APOE ε4+ × Years to Onset	0.017	(−0.028, 0.063)	0.4545

^*p < 0.05

^**p < 0.01

^***p < 0.001

CI= confidence interval