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. Author manuscript; available in PMC: 2020 Apr 27.
Published in final edited form as: Rev Environ Health. 2018 Sep 25;33(3):247–264. doi: 10.1515/reveh-2017-0033

Table 1:

Summary of the animal studies literature.

Reference Subjects (n) Pollutants analyzed Results
Dominickand Carson (19) 18 Sows CO Ambient CO level, ppm Live births Stillbirths Stillbirths, %
Control 22 1 4.3
150 13 0 0
200 14 1 6.7
250 15 8 34.8
300 15 11 42.3
350 5 20 80
Mohallem et al. (20) 40 Female mice PM10, NO2 Chamber Live-born pups Live-born pups per mouse (median) Reabsorptions/fetal deaths per mouse (median)
Clean 106 6 1
Polluted 75 4 2
Pejsak et al. (21) 1100 Sows CO Farrowing unit Number of sows that aborted
D (January 2006) 28/28
D (March 2006) 25/28
H 26/28
Rigdon and Rennels (22) 14 Female rats Benzo[a]pyrene Untreated Treated
Successful births 3 1
Unsuccessful births 3 8
Tsukue et al.(23) 60 Female mice DEP Diesel exhaust particle concentration, mg/m3
Control (0.0) 0.3 1.0 3.0
Number of abortions, % 0 (0%) 1 (9.1%) 1(10.0%) 2(16.7%)
Waldner et al. (24) 23 Herds of cattle H2S Health measure Investigational herds (n = 18) Control herds (n = 5)
Abortion risk 0.0 (0.0–3.0) 0.0 (0.0–3.9)
Stillbirth risk 1.6(0.0–6.0) 1.9(1.3–3.3)
*Data expressed as median % (range %)
Waldner (25) 28,144 Cows for abortion assessment, 28,402 Calves for stillbirth assessment SO2, H2S, VOC Summary risk for study population
Productivity outcome % n
Risk of abortion 2.6 739
Risk of stillbirth 2.6 739
Wood (26) 16 Sows CO Incident Total piglets born Piglets dead at birth (% of total)
Incident 1 1198 335(28%)
Incident 2 68 36 (52.9%)