Table 1.
Clinical and radiological data of the study cohort regarding study inclusion and 3-month outcome
| Study cohort | Excluded patients | p value | Study cohort | |||
|---|---|---|---|---|---|---|
| mRS 0–2 | mRS 3–6 | p value | ||||
| n = 115 | n = 101 | n = 59 (51.3%) | n = 56 (48.7%) | |||
| Clinical data | ||||||
| Age (mean ± SD) | 65.3 ± 13.0 | 66.7 ± 13.9 | 0.43 | 62.1 ± 13.8 | 68.7 ± 11.1 | 0.001 |
| Male sex | 64 (55.7%) | 51 (50.5%) | 0.53 | 31 (52.5%) | 33 (58.9%) | 0.49 |
| Hypertension | 72 (62.6%) | 67 (66.3%) | 0.66 | 29 (49.2%) | 43 (76.8%) | 0.002 |
| Dyslipidaemia | 17 (14.8%) | 20 (19.8%) | 0.33 | 7 (11.9%) | 10 (17.9%) | 0.37 |
| Chronic heart diseasea | 17 (14.8%) | 17 (16.8%) | 0.55 | 5 (8.5%) | 12 (21.4%) | 0.05 |
| Diabetes | 16 (13.9%) | 23 (22.8%) | 0.06 | 3 (5.1%) | 13 (23.2%) | 0.005 |
| Atrial fibrillation | 48 (41.7%) | 40 (39.6%) | 0.85 | 22 (37.3%) | 26 (46.4%) | 0.32 |
| Prestroke mRS (median, IQR) | 0 (0) | 0 (0) | 0.47 | 0 (0) | 0 (0) | 0.13 |
| Stroke of unknown symptom onset | 27 (23.5%) | 13 (12.9%) | 0.05 | 11 (18.6%) | 16 (28.6%) | 0.21 |
| NIHSS at admission (median, range) | 14 (4–25) | 15 (6–34) | 0.01 | 13 (4–22) | 16 (8–25) | < 0.001 |
| Radiological findings | ||||||
| MCA/M1-occlusion | 87 (75.7%) | 76 (75.2%) | 0.95 | 44 (74.6%) | 43 (76.8%) | 0.78 |
| MCA/M2-occlusion | 13 (11.3%) | 4 (4.0%) | 0.05 | 7 (11.9%) | 6 (10.7%) | 0.85 |
| Intracranial ICA occlusion | 11 (9.6%) | 18 (17.8%) | 0.08 | 5 (8.5%) | 6 (10.7%) | 0.68 |
| CTA collateral scoring (TAN, median, range) | 2 (0–3) | 2 (0–3) | 0.16 | 2 (0–3) | 1 (0–3) | 0.04 |
| ASPECTS pre-intervention (median, range) | 9 (5–10) | 9 (3–10) | 0.20 | 9 (5–10) | 9 (3–10) | 0.05 |
| Intervention | ||||||
| Intravenous thrombolysis | 69 (60%) | 68 (67.3%) | 0.43 | 39 (66.1%) | 30 (53.6%) | 0.17 |
| Time to groin puncture (min, median, IQR) | 200, 82 | 205, 84 | 0.56 | 203, 81 | 197, 74 | 0.55 |
| Time to recanalization (min, median, IQR) | 260, 93 | 271, 90 | 0.36 | 254, 92 | 272, 77 | 0.68 |
| Anaesthesia duration (min, median, IQR) | 112, 64 | NA | NA | 108, 54 | 131, 67 | 0.02 |
| Successful recanalization (TICI 2b–3) | 96 (83.5%) | 82 (81.2%) | 0.43 | 56 (94.9%) | 40 (71.4%) | 0.001 |
| ASPECTS post-interventionb (median, range) | 5 (0–9) | 5 (0–9) | 0.41 | 6 (2–9) | 3 (0–8) | < 0.001 |
ASPECTS Alberta stroke program early CT scores, CTA computed tomography angiography, ICA internal carotid artery, MCA middle cerebral artery, NIHSS National Institutes of Health Stroke Severity Scale, mRS modified Rankin Scale, TICI thrombolysis in cerebral infarction
aCoronary artery disease, heart failure, cardiomyopathy or valve disease
bAt follow-up imaging 24 h post-stroke