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. 2020 Mar 4;267(5):1554–1566. doi: 10.1007/s00415-020-09728-0

Table 3.

Thunderclap headache

Publication N Mean Follow-up (years) Past TCHA % Recurrent TCHA % Subsequent primary HA % Prior primary HA% Precipitant to onset Duration Additional features (%)

Wijdicks 1988 [22]

PTCHA

71 3.3 10 17 44 Cough 7%, sex 4%, other exertion 17%, light tasks 72%

8–24 h median

Range 1 h to 1 week

Vomiting (38), diplopia (3), stiff neck (14), dilated pupil (1)

Harling  1989 [23]

PTCHA

14 1.5 to 2.5 (no mean given) 93 28 Exercise, weights, sex 21%

 < 2 h 0%

 > 2 h 79%

Vomiting (28) (P < 0.02),

Neck stiffness (57)

Photophobia (64)

Loss of consciousness (14)

Harling 1989 SAH 35 43 Exercise, weights, sex 28%

Vomiting (72)

Neck stiffness (80)

Photophobia (57)

Loss of consciousness (34)

Markus [24]

PTCHA

18 1.7 25 25 50 38

N (19%)

Sex 1

Straining 1

Lifting 0

Diving 1

Nausea (88)

Vomiting (44)

Photophobia (50)

Collapse (6)

Markus 1991

SAH

37 60

N (18%)

Sex 1

Straining 0

Lifting 1

Diving 1

Nausea (60)

Vomiting (68)

Photophobia (5)

Collapse (16)

Linn 1998 [8]

PTCHA

42 Data from first presentation only 14 57 Exertion/Valsalva 22%

Nausea (76)

Vomiting (43)

Transient loss/clouding of consciousness (16)

Transient focal symptoms* (22)

Seizure 0%

Linn 1998

SAH

37 19 38 Exertion/Valsalva 50%

Nausea (76)

Vomiting (69)

Transient loss/clouding of consciousness (26)

Transient focal symptoms* (33)

Seizure (7)

Landtblom 2002 [9]

PTCHA

101 1 29 24

28 Migraine

25 TTH

Exertion/Valsalva 21%

Sexual TCHA 9%

Nausea (91)

Neck stiffness (61)

Paresis (13)

Impaired consciousness (17) Unconsciousness (17)

Photophobia (9)

Blurred vision (4)

Scintillation scotoma (0)

Diplopia (0)

Landtblom 2002 SAH 23 17

22 Migraine

9 TTH

Exertion/Valsalva 17%

Sexual TCHA 9%

Nausea (61)

Neck stiffness (10)

Paresis (3)

Impaired consciousness (9) Unconsciousness (4)

Photophobia (4)

Blurred vision (4)

Scintillation scotoma (7)

Diplopia (2)

PTCHA Primary thunderclap headache, SAH Subarachnoid haemorrhage

*Transient neurological symptoms—double vision, speech arrest, sensory phenomena or weakness in the face or limbs (unilateral or bilateral), and difficulties with walking