Table 2.
Change in NT-proBNP Values by Comorbidities and Echocardiographic Parameters in the Three Arms
| NT-proBNP Value (pg/mL) | All Patients | LVEF < 40% | LVEF 40–49% | LVEF ≥ 50% | p value | |
|---|---|---|---|---|---|---|
| Creatinine clearance | 30–59 | 4647.76±6618 (2073) | 7304.27±9062 (2572) | 4404.4 ± 3786 (3000) | 1536.1 ±973 (1100) | NS |
| 60–89 | 2575.31±2184 (2019.5) | 2434. ±2839 (982) | 1767.06±1223 (1314) | 3288.11±2477 (2793) | NS | |
| ≥90 | 2036.78±2314 (1184) | 2945.18±2871 (1669) | 1574.06±1735 (1254) | 1790. 89 ±2189 (1021) | NS | |
| Atrial fibrillation | Mean ± SD (median) | 3306.50±4598 (1912) | 5878±8077 (2572) | 1851.83±1815 (1125) | 2906.87 ±2710 (2039) | 0.032 Significant differences between group 1 vs group 2 and group 1 vs group 3 |
| Diabetes mellitus | Yes | 2460.90±3383.68 (1317) | 5226.33± 5969 (2138) | 1139.5±604.93 (1317) | 1953.3±2009 (1176) | 0.014 Significant differences between group 1 vs group 2 and group 1 vs group 3 |
| No | 2817.58±3831.87 (1505) | 4026.21±6137 (1692) | 2396.84±2377.66 (1421) | 2424.87±2399.9 (1572) | NS | |
| Arterial hypertension | Yes | 2550.91±3552 (1556) | 4266.47±6879 (1692) | 1994.76±2031 (1320) | 2211.8±1944 (1590) | 0.08 |
| No | 3145.13±4002 (1188) | 4474±5109 (2296) | 2167.63±2383 (1404) | 2310.54±3313 (893) | NS | |
| Overweight | 3072.66±2781 (2000) | 6103.33±4713 (8645) | 1645.2±1521 (1067) | 2793.42±1651 (2527) | 0.07 | |
| 1st degree obesity | 2873.42±4472 (1339) | 5102.40±8101 (1184) | 2106±1831.4 (1833) | 2166.19±2127 (1233) | NS | |
| 2nd degree obesity | 2759.37±2957 (1525.5) | 3847.44±3536 (2612) | 2815.1±3068 (1653.5) | 1963.23±2371 (1108) | NS | |
| 3rd degree obesity | 1789.43±2225 (1119) | 2033.4±1802 (1692) | 957.5±489.75 (936) | 2543.8±3632 (924) | NS | |
| Smoking | Yes | 2814±2884 (1320) | 3535.45±3563.7 (1184) | 2509.33±2304 (1757) | 2653.71±2946 (1115) | NS |
| No | 2675.87±4117 (1404) | 4797.61±7016 (2296) | 1717.76±1952 (1067) | 1977.68±1685 (1501) | NS | |
| Left atrium dilated (>40 mm) | Yes | 3026.56±4037 (1724.5) | 4829.36±6594 (2296) | 2069.4±2211 (1379) | 2627.65±2487 (2000) | NS |
| No | 1705.35±1776 (1095) | 2700.85±3015 (1120) | 1938.5±1681 (1235) | 1147.53±572.85 (1021) | NS |
Note: p < 0.05 was statistically significant.