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. 2020 Apr 21;15:547–556. doi: 10.2147/CIA.S248158

Table 3.

Medical Treatment of Patients Stratified by LVEF

Total All Patients LVEF < 40% LVEF 40–49% LVEF ≥ 50% p value
126 32 37 57
Angiotensin converting enzyme inhibitors (ACEIs) – No (%) 75 (59.5%) 15(46.8%) 19(51.3%) 41(71.9%) 0.0340
Angiotensin AT1 receptor blockers (ARBs) – No (%) 49 (38.8%) 22(68.7%) 9(24.3%) 18(31.5%) 0.0054
Sacubitril/valsartan – No (%) 12 (9.5%) 8(25%) 1 (2.7%) 0(0) 0.0018
Beta-blockers – No (%) 121(96%) 30(93.7%) 35(94.5%) 56 (98.2%) NS
Ivabradine – No (%) 10 (7.9%) 4 (12.5%) 4 (10.8%) 2(3.5%) NS
Long-lasting nitrates – No (%) 28(22.2%) 2(6.2%) 23(62.1%) 3 (5.2%) <0.0001
Calcium channel blockers – No (%) 6 (4.7%) 3 (9.3%) 1(2.7%) 2(3.5%) NS
Antiarrhythmics – No (%) 39 (30.9%) 8 (25%) 11(29.7%) 20(35%) NS
Anti-aldosterone agents (MRAs) – No (%) 69 (54.7%) 30 (93%) 28 (75%) 11 (19%) NS
Anticoagulants – No (%) 72 (57.1%) 20(62.5%) 19(51.3%) 33(57.8%) NS

Note: p < 0.05 was statistically significant.