Table 1.
Characterization of NPs Preparations
| NPs Preparations | GBP % of TPGS | Mean Particle Size (nm) | Mean Zeta Potential (mV) | Polydispersity Index (PDI) | BA Loading Efficiency (%) | BA Encapsulation Efficiency (%) | C60(OH)n Loading Efficiency (%) | C60(OH)n Encapsulation Efficiency (%) |
|---|---|---|---|---|---|---|---|---|
| Batch A | 1% | 226.9±26.8a | −7.05±0.58a | 0.311±0.011a | 2.489±0.014a | 47.81±2.41a | 2.450±0.021a | 46.32±3.43a |
| Batch B | 5% | 229.2±23.1a | −7.04±0.62a | 0.305±0.010a | 3.449±0.042b | 57.96±3.94b | 3.351±0.018b | 54.04±5.04b |
| Batch C | 10% | 220.4±22.0a | −6.98±0.53a | 0.279±0.012b | 4.695±0.119c | 66.89±4.09c | 4.620±0.322c | 64.38±2.52c |
| Batch D | 15% | 205.5±20.5b | −6.84±0.69b | 0.255±0.009c | 7.031±0.252d | 80.05±6.56d | 6.878±0.427d | 80.02±3.67d |
| Batch E* | 20% | 191.1±21.2c | −6.80±0.78b | 0.251±0.021c | 9.059±0.598e | 92.89±5.21e | 8.013±0.612e | 86.58±2.59e |
| Batch F | 25% | 231.0±25.7a | −6.59±0.65c | 0.264±0.015d | 8.772±0.761f | 90.97±2.43e | 7.841±0.389e | 84.90±4.47e |
| Batch G | 30% | 359.8±31.1d | −6.62±0.32c | 0.238±0.018e | 8.001±0.531g | 85.10±4.65f | 7.081±0.627d | 78.95±2.25d |
Notes: Data are expressed as mean ± SD (n=3). *Optimized batch was batch E (20% GBP of TPGS, w%). GBP: BA: C60(OH)n ratio (2:1:1, w/w/w). C60(OH)n (mixture with n=2–6, n=10–14 and n=16–20, 1:1:1, w/w/w). Values not sharing the equal letter are obviously diverse from each other (p < 0.05 ANOVA ensued by the Tukey’s test).