. 2020 Apr 22;15:2751–2764. doi: 10.2147/IJN.S238536

Table 1.

Characteristics of DOX-Loaded Complexes

Complexes	Conjugated Number per PAMAM^a			Size^b (nm)	Zeta^b (mV)	DOX^c
Complexes	His	PEG	Tf	Size^b (nm)	Zeta^b (mV)	EE%	DL%
P-PEG/DOX	-	15	-	11.50 ±0.36	2.14 ± 0.28	85.3 ± 1.5	9.4 ± 0.4
HP-PEG/DOX	25	13	-	13.05 ±0.10	3.12 ± 0.46	87.8 ± 1.7	11.1 ± 0.2
HP-ss-PEG/DOX	25	12	-	14.24 ±0.65	3.54 ± 0.18	86.6 ± 2.5	10.7 ± 0.2
HP-ss-PEG-Tf/DOX	25	12	1.5	22.09 ±0.48	−2.94 ±0.53	80.6 ± 1.6	9.6 ± 0.1

Notes: ^aDetermined by ¹H NMR; ^bDetermined by Nicomp 380 ZLS; ^cDetermined by UV-vis spectrometry.