Fig. 6.

Excitatory neurons reduced after Egr1 knockout. A) Predicted cell-type compositions in Egr1 knockout and 6-week old mouse cortex. B) Volcano plot shows a comparison of the expression level of excitatory neuron marker genes in Egr1KO and 6-week old cortexes. The points colored in red represent the differentially expressed genes in Egr1KO compared to 6-weeks old cortex and the size of the points represents the fold change of expression in excitatory neurons compared to other cell types. C) Go enrichment analysis of the differentially expressed excitatory neuron markers in Egr1KO. The point size represents the number of genes enriched. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)