Table 4.
Contents of TC, FC and CE in human primary macrophage-derived foam cells measured by HPLC (μg/mg cell protein).
| Group | TC | FC | CE | CE/TC (%) |
|---|---|---|---|---|
| sh-NC | 443.56 ± 21.35 | 176.25 ± 11.37 | 267.38 ± 15.66 | 60.37 |
| sh-CDKN2B | 631.35 ± 30.15a | 231.58 ± 14.68a | 400.78 ± 18.59a | 63.64 |
| sh-CDKN2B-AS1 + sh-CDKN2B | 457.32 ± 13.48b | 171.25 ± 9.57b | 286.97 ± 12.33b | 62.73 |
Note:
a
p < 0.05 vs. the sh-NC group.
b
p < 0.05 vs. the sh-CDKN2B group. All the experiments were repeated 3 times independently, and the data among multiple groups were analyzed by one-way analysis of variance; sh-NC, cells transduced with pSIH1-H1-copGFP-sh-NC; sh-CDKN2B, cells transduced with pSIH1-H1-copGFP-sh-CDKN2B; sh-CDKN2B-AS1, cells transduced with pSIH1-H1-copGFP-sh-CDKN2B-AS1; TC, total cholesterol; FC, free cholesterol; CE, cholesterol ester.