Table 6.

The weights and lipid levels of ApoE^−/− mice with different treatments of CDKN2B-AS1 and CDKN2B (n = 12).

Group	Weight (g)	TC (mmol/L)	TG (mmol/L)	LDL (mmol/L)
sh-NC	28.14 ± 1.70	6.98 ± 0.79	2.61 ± 0.31	3.93 ± 0.58
sh-CDKN2B-AS1	27.70 ± 0.82	3.18 ± 0.62a	1.61 ± 0.22a	2.02 ± 0.49a
sh-CDKN2B	28.49 ± 1.31	13.73 ± 1.17a	3.62 ± 0.25a	7.33 ± 0.84a
sh-CDKN2B-AS1 + sh-CDKN2B	28.70 ± 1.34	7.30 ± 0.90b	2.65 ± 0.27b	4.14 ± 0.64b

Note:

^ap < 0.05 vs. the sh-NC group.

^bp < 0.05 vs. the sh-CDKN2B group. All the experiments were repeated 3 times independently, and the data among multiple groups were analyzed by one-way analysis of variance; sh-NC, mice injected with pSIH1-H1-copGFP-sh-NC; sh-CDKN2B, mice injected with pSIH1-H1-copGFP-sh-CDKN2B; sh-CDKN2B-AS1, mice injected with pSIH1-H1-copGFP-sh-CDKN2B-AS1; sh-CDKN2B-AS1 + sh-CDKN2B, mice injected with pSIH1-H1-copGFP-sh-CDKN2B-AS1 and pSIH1-H1-copGFP-sh-CDKN2B; TC, total cholesterol; TG, triglyceride; LDL, low density lipoprotein.