Figure 7.31.

RNA recombination. Panel (A): Three classes of RNA recombination. Replicase-mediated RNA synthesis after the template-switch event is shown by an arrow. The hairpin structure shown on the acceptor RNA symbolically represents various RNA structures that are required for class-2 and -3 recombination. From Nagy and Simon (1997) with permission of the publishers. Panel (B): Replicase-mediated template-switching models of RNA recombination in TCV and BMV. Subpanel (a): Heteroduplex-mediated recombination between (+) strands of BMV RNA1 and RNA3. Subpanel (b): Recombination between satellite RNAs associated with TCV. The sequence of the required motif 1-hairpin is shown. Subpanel (c): Recombination events within the identical regions of BMV RNA2 and RNA3. Recombination is favored when GC-rich and AU-rich sequences are located as shown.

From Nagy and Simon (1997) with permission of the publishers.