Table 3.
Neuroprotective effect of SNL on acetylcholine and acetylcholinesterase levels in ALB induced ICH-IVH in rats.
| Groups | AchE | Ach |
|---|---|---|
| (μmol/mg protein) | (μmol/mg protein) | |
| Sham Control | 4.33 ± 3.67 | 8.71 ± 0.56 |
| SNL60 Perse | 4.33 ± 3.67 | 8.63 ± 0.95 |
| ALB | 94.5 ± 6.41* | 0.21 ± 0.11* |
| ALB + SNL40 | 79.67 ± 8.86# | 1.45 ± 0.45# |
| ALB + SNL60 | 65.0 ± 8.87#@ | 2.71 ± 0.18#@ |
| ALB + SNL60 + PGB30 | 51.17 ± 6.49$ | 3.96 ± 0.56$ |
| ALB + SNL60 + CLB20 | 37.2 ± 10.08$ | 5.38 ± 0.79$ |
| ALB + SNL60 + MEM20 | 23.1 ± 5.29$ | 6.63 ± 0.72$ |
| ALB + SNL60 + DNP3 | 9.23 ± 2.280$β | 8 ± 0.70$β |
Data expressed as mean ± SEM (n = 6). * p < 0.05 versus sham control and SNL60 perse; # p < 0.05 versus ALB; #@ p < 0.05 versus ALB + SNL40; $ p < 0.05 versus ALB + SNL60; $β p < 0.05 versus MEM20, CLB20 and PGB30 (One way ANOVA followed by Tukey’s post hoc test).