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. Author manuscript; available in PMC: 2020 Apr 27.
Published in final edited form as: Endocrinol Metab Clin North Am. 2019 Sep 19;48(4):765–778. doi: 10.1016/j.ecl.2019.08.007

Table 2:

Clinical findings associated with renovascular disease: Data from 2005 American College of Cardiology/American Heart Association guidelines. (Hirsch AT, Haskal ZJ, Hertzer NR, et al. ACC/AHA 2005 Practice Guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. Circulation 2006;113:e463–654.)

Clinical Findings Associated with Renovascular Disease
Onset hypertension before age of 30 years old
Accelerated, resistant, malignant hypertension
Deterioration of renal function in response to angiotensin- converting enzyme inhibitors or angiotensin-receptor blocker
New onset of hypertension after 50 years of age (suggestive of atherosclerotic renal artery stenosis)
Asymmetric kidneys with more than 1.5 cm of difference in the size and otherwise unexplained loss of kidney function
Sudden unexplained pulmonary edema