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. 2020 Apr 27;11(4):292. doi: 10.1038/s41419-020-2491-3

Fig. 7. A dual role model for the cellular functions of INPP4B.

Fig. 7

INPP4B exerts its antitumor activity through suppression of Akt-mTOR signaling, as well as promotion of Rad50 mediated DNA double strand break repair. A green line with an arrow indicates activation and a red line with a slash depicts inhibition. For more details see the related text in the discussion section.