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. 2020 Apr 27;10:7075. doi: 10.1038/s41598-020-64042-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Improved muscle histology in mdx mice exposed to young WT peripheral circulation. (A) H&E staining and (B) trichrome staining, representative image shows the gastrocnemius, tibialis anterior, diaphragm muscle and cardiac tissue of mdx mice. (C) Quantification of the myofiber area between the parabiont mdx and control mdx muscle. The average number of myofibers of each size range calculated from >1,000 fibers analyzed per mdx muscle (n = 6). (D) Quantification of collagen positive area. Error bars indicate ‘mean + SD’, n = 6, *p < 0.05. Scale bar = 100 µm.