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. 2020 Apr 27;10:7081. doi: 10.1038/s41598-020-62849-4

Table 3.

Clinical symptoms of study participants based on participant report of symptoms experienced during current illness, Endulen Hospital, Tanzania, 2016–2017.

Case population n/N (%) Non-case population n/N (%) OR (95% CI) OR p value
Symptom
Reported fever in past 2 weeks 13/14 (92.9) 212/215 (98.6) 0.18 (0.02–3.86) 0.16
Fever type Continuous 0/13 (0.0) 9/211 (0.04) Ref
Intermittent 13/13 (100) 202/211 (95.8) Inf (-Inf – Inf) 0.99
Unit of fever duration Days 11/13 (84.6) 192/211 (91.0) Ref
Months 2/13 (15.4) 16/211 (7.58) 2.18 (0.32–9.1) 0.34
Years 0/13 (0.0) 3/211 (1.42) 0.00 (-Inf – Inf) 0.99
Night sweats 13/14 (92.9) 140/210 (66.0) 6.50 (1.26–119.3) 0.07
Fatigue 11/14 (78.6) 192/213 (90.1) 0.40 (0.11–1.87) 0.19
Joint pain 12/14 (85.7) 190/210 (90.5) 0.63 (0.16–4.24) 0.56
Swollen joints 3/14 (21.4) 30/209 (14.4) 1.63 (0.36–5.58) 0.47
Myalgia 5/13 (38.5) 83/201 (41.3) 0.89 (0.26–2.76) 0.84
Back pain 6/14 (42.9) 152 /213 (71.4) 0.30 (0.10–0.90) 0.03
Headache 12/14 (85.7) 185/214 (86.4) 0.93 (0.24–6.24) 0.93
Anorexia 7/14 (50.0) 105/215 (48.8) 1.05 (0.35–3.16) 0.93
Clinical Management
Presumptive diagnosis including brucellosis 6/13 (46.2) 32/175 (18.3) 3.83 (1.16–12.30) 0.02
Admission to hospital 3/14 (21.4) 7/177 (4.0) 6.62 (1.30–27.75) 0.01
Initial treatment for brucellosis 4/14 (28.6) 12/216 (5.6) 6.80 (1.68–23.91) <0.01

Reported % reflects the denominator appropriate for each symptom. Univariable analysis odds ratio (OR), 95% confidence intervals (CI) and p values are given. OR, CI and p values reported to two decimal places.