Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 27;10:7085. doi: 10.1038/s41598-020-62911-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Group separation by selected metabolites with high Variable Importance for Projection (VIP) scores. Multilevel PLS-DA models were fitted on all samples using a selection of 46 metabolites which reached VIP scores of ≥2 and associated regression coefficients of ≤−0.1 or ≥0.1 in any pairwise PLS-DA model described in Fig. 2. Score plots of the resulting model for M1 (A) and M2 (C) macrophages (M2) are displayed. Untreated samples are depicted as green squares, LPS stimulated samples as blue triangles and Mtb infected samples as red dots. Shade of symbol color reflects time point (4 h = light, 24 h = dark). Strongly correlated metabolites (threshold: ≥0.5) are displayed in circle plots for both the M1 (B) and the M2 (C) PLS-DA model.