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AAV9 and AAVrh10 Particles Shedding in the Serum and CSF
(A and B) AAV viral genome shedding was analyzed at time points 0 (before injection), 7, and 19 days after vector administration in NHPs CSF (A) and in serum at time points 0, 1 h, and 3, 7, 10 and 19 days post-injection (B). DNA viral genome increase after AAV LIT-KT and ICV injection showed the presence of AAV particles in serum and CSF and was expressed as percentage of injected total dose.
