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. 2020 Apr 27;10:7072. doi: 10.1038/s41598-020-63306-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Graphical summary of the variations. All metabolites that were significantly changed due to the factor Atherosclerosis, or the factor Colchicine, or both are gathered. Ordinates represent log₂(FC) between the compared groups: Pannels (A,C,E), changes 36 weeks vs. 18 weeks, without colchicine (atherosclerosis progression); Pannels (B,D,F), changes 36 weeks with colchicine vs. 36 weeks without colchicine. Codes for metabolites as in Table 2.