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HN878 infection induces differential expression of cytokines and chemokines around lung granulomas. C57BL/6 mice were infected with Mycobacterium tuberculosis (Mtb) H37Rv (Rv) or Mtb HN878 (HN) as described in Figure 1. (A) The expression of CXCL13, (B) STAT-1, (C) CCL2, and (D) interferon-β (IFN-B) was determined by in situ hybridization of messenger ribonucleic acid on formalin-fixed and paraffin-embedded slides.
