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. 2020 Apr 20;10:508. doi: 10.3389/fonc.2020.00508

Figure 4.

Figure 4

Prognostic significance of the 12-gene signature derived risk scores in TCGA cohort. (A–C) Prognosis efficiency of the 12-gene risk signature in all grades (A), LGG (B) and GBM (C) in TCGA cohort. (D–I) Outcome prediction of the 12-gene signature in patients stratified by IDH status (D,E), MGMT promoter status (F,G) and EGFR status (H,I) in TCGA cohort. (J–K) Kaplan–Meier survival curves for LGG patients with IDH-mutant (J) and IDH-wildtype (K), classified into two groups based on 12-gene signature derived risk scores. (L–M) Kaplan–Meier survival curves for GBM patients with IDH-mutant (L) and IDH-wildtype (M), classified into two groups based on 12-gene signature derived risk scores. LGG, lower-grade glioma; GBM, glioblastoma; OS, overall survival.