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. 2020 Apr 2;19(6):3571–3580. doi: 10.3892/etm.2020.8635

Figure 3.

Figure 3

mRNA expression of VEGF-C, VEGF-D, MMP-1 and MMP-7 in non-small cell lung cancer cell lines. (A) Expression of VEGF-C, VEGF-D, MMP-1 and MMP-7 in A549 cells significantly increased after CCL25 treatment, and the addition of an anti-CCR9 antibody inhibited CCL25-mediated upregulation. (B) Expression of VEGF-C, VEGF-D, MMP-1 and MMP-7 in SK-MES-1 cells increased after CCL25 treatment, and the anti-CCR9 antibody abrogated this CCL25-mediated increase. *P<0.05. CCR9, CC chemokine receptor 9; CCL25, CC motif chemokine ligand 25; VEGF, vascular endothelial growth factor; MMP-1, matrix metalloproteinase-1; MMP-7, matrix metalloproteinase-7.