Table 1. Relationship between TPT1-AS1 expression and clinicopathologic features of CRC patients (n=80).
Variable | Relative TPT1-AS1 expression | P-value | |
Low (n=40) | High (n=40) | ||
Age | NS | ||
<50 | 25 | 19 | |
>50 | 15 | 21 | |
Gender | NS | ||
Male | 22 | 26 | |
Female | 18 | 14 | |
Histological differentiation | NS | ||
Well | 16 | 12 | |
Moderate | 13 | 19 | |
Poor | 11 | 9 | |
Primary tumor sites | NS | ||
Ascending colon | 11 | 7 | |
Transverse colon | 7 | 5 | |
Descending colon | 3 | 6 | |
Sigmoid colon | 8 | 9 | |
Rectum | 11 | 13 | |
Tumor size | P<0.05 | ||
<5cm | 24 | 13 | |
>5cm | 16 | 27 | |
Lymph node metastasis | P<0.01 | ||
Yes | 17 | 29 | |
No | 23 | 11 | |
Distant metastasis | P<0.01 | ||
Yes | 14 | 28 | |
No | 26 | 12 | |
Tumor stage | P<0.01 | ||
I-II | 19 | 8 | |
III-IV | 21 | 32 |
Note: CRC patients were divided into TPT1-AS1 high group and low group according to the analysis of qRT-PCR detection. NS, not significant between different groups. Differences among variables were evaluated by χ2 or Fisher’s exact χ2-test.