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Spermidine and spermine depress apoptosis in SAMP8. (A) The western blot of apoptotic protein. (B) The expression of Bax and Bcl-2 in the brain. (C) The expression of Caspase-3 in the brain. (D) TUNEL staining in cortex. Scale bar: 50μm. Data represent mean ± SEM (n = 3 per group). #P < 0.05, ##P < 0.01, ###P < 0.001 vs. SAMR1; *P < 0.05, **P < 0.01, ***P < 0.001 vs. SAMP8.
