Table 1. General characteristics of CRC-specific immune-related genes.
| Gene symbol | logFC | FDR | HR | P-value |
| NGF | -1.07762 | 1.11E-07 | 3.614874 | 1.12E-05 |
| FABP4 | -1.69607 | 2.65E-17 | 1.013513 | 4.75E-05 |
| NGFR | -1.7335 | 2.53E-16 | 1.200272 | 0.000161 |
| ADIPOQ | -1.99025 | 9.61E-18 | 1.101961 | 0.000222 |
| OXTR | 2.970949 | 1.70E-20 | 1.426463 | 0.000285 |
| SEMA3G | -1.98005 | 7.35E-19 | 1.294111 | 0.000355 |
| INHBA | 5.410219 | 6.03E-22 | 1.052935 | 0.000678 |
| IGHG1 | 2.242033 | 0.000217 | 1.000558 | 0.000825 |
| PTH1R | -1.97323 | 3.73E-19 | 1.628333 | 0.000936 |
| VIP | -3.35624 | 2.99E-21 | 1.057744 | 0.001913 |
| IGKV1-33 | -2.0014 | 3.50E-15 | 1.030337 | 0.001979 |
| IGHV5-51 | -2.04671 | 3.90E-15 | 1.001624 | 0.002062 |
| IGKV1-8 | -1.96614 | 2.74E-15 | 1.044039 | 0.002316 |
| RETNLB | -1.11809 | 4.48E-13 | 1.003827 | 0.002823 |
| UCN | 2.370658 | 2.94E-17 | 1.383005 | 0.002826 |
| PLCG2 | -1.81429 | 6.39E-19 | 1.67407 | 0.002941 |
| IGKV2D-40 | -1.04607 | 1.15E-10 | 1.015759 | 0.003079 |
| IGLV6-57 | -1.60553 | 4.76E-12 | 1.001968 | 0.003346 |
| NPR1 | -1.70244 | 3.59E-16 | 1.50082 | 0.00463 |
| NOX4 | 3.263304 | 5.66E-18 | 1.643741 | 0.00513 |
| CCL19 | -2.15933 | 9.35E-15 | 1.029576 | 0.005852 |
| F2RL1 | -1.11351 | 1.65E-17 | 0.966769 | 0.006461 |
| STC1 | 2.269389 | 2.56E-16 | 1.078088 | 0.0072 |
| CXCL3 | 3.047496 | 4.68E-18 | 0.976418 | 0.007315 |
| CD1B | 1.090892 | 0.012274 | 0.057461 | 0.007658 |
| SLC10A2 | -7.37303 | 2.19E-25 | 1.832561 | 0.007661 |
| IGHV4-31 | -1.69851 | 9.17E-11 | 1.008218 | 0.007668 |
| IGHG4 | 1.769556 | 0.02942 | 1.000463 | 0.008256 |
| TRDC | -1.85546 | 1.40E-15 | 1.14881 | 0.008409 |
| FGF2 | -1.37298 | 1.56E-11 | 1.340343 | 0.009 |
| NR3C2 | -2.59095 | 7.31E-22 | 0.8063 | 0.011706 |
| SCG2 | -2.14034 | 2.39E-19 | 1.118764 | 0.012272 |
| CCL28 | -1.9804 | 6.46E-18 | 0.923295 | 0.012702 |
| TNFSF12 | -1.14925 | 1.37E-12 | 1.101101 | 0.015819 |
| SLIT2 | -1.69869 | 2.77E-14 | 1.407394 | 0.016025 |
| CXCL12 | -2.54566 | 4.83E-21 | 1.062678 | 0.01692 |
| IGHV2-70 | -1.45759 | 9.83E-11 | 1.014614 | 0.017613 |
| PTGDS | -1.35298 | 7.22E-12 | 1.035543 | 0.01783 |
| CLCF1 | 1.016493 | 3.25E-10 | 1.118713 | 0.018123 |
| BID | 1.147326 | 2.83E-18 | 0.937667 | 0.018657 |
| CXCL1 | 2.94518 | 3.55E-17 | 0.993112 | 0.019735 |
| XCL1 | -1.02275 | 1.65E-09 | 1.652723 | 0.019766 |
| PROCR | 1.21046 | 4.01E-11 | 0.981309 | 0.020768 |
| FGFR2 | -2.15905 | 2.28E-20 | 1.101962 | 0.021634 |
| CD79B | -2.05831 | 1.30E-16 | 1.112374 | 0.023507 |
| CD19 | -1.8624 | 2.94E-11 | 1.263127 | 0.025436 |
| S100P | 2.517715 | 3.23E-16 | 0.997402 | 0.028846 |
| IL1RAP | 1.053287 | 5.06E-13 | 1.71503 | 0.030956 |
| GUCA2A | -5.04559 | 7.70E-22 | 0.988757 | 0.031143 |
| BIRC5 | 1.625605 | 2.98E-19 | 0.96511 | 0.031986 |
| IGLV1-36 | -1.61723 | 5.61E-15 | 1.006035 | 0.033026 |
| IGLC3 | -1.8978 | 5.95E-13 | 1.000929 | 0.033267 |
| CHP2 | -3.81304 | 1.80E-21 | 0.971156 | 0.033524 |
| IGHV3-64 | -1.38936 | 7.61E-14 | 1.00211 | 0.034568 |
| IL13RA2 | 1.365327 | 0.000112 | 0.516776 | 0.034577 |
| IGHV3-38 | -1.95173 | 1.53E-14 | 1.050918 | 0.03483 |
| IGHV4-4 | -2.60452 | 1.40E-15 | 1.043988 | 0.035024 |
| S1PR1 | -1.03942 | 2.45E-13 | 1.105949 | 0.035328 |
| COLEC12 | -1.7569 | 5.08E-18 | 1.230376 | 0.035387 |
| KL | -1.1424 | 5.26E-16 | 1.191899 | 0.035919 |
| GCG | -4.9816 | 5.83E-22 | 1.017926 | 0.03803 |
| JAG2 | 2.065779 | 1.29E-17 | 1.033744 | 0.038079 |
| TLR7 | -1.74294 | 1.68E-17 | 2.178313 | 0.038773 |
| TNFRSF13C | -1.60074 | 1.90E-08 | 1.35185 | 0.03901 |
| IGHV1-24 | -1.00006 | 3.78E-08 | 1.003218 | 0.040381 |
| PYY | -5.71 | 6.50E-22 | 0.766028 | 0.042196 |
| GRP | 2.434638 | 9.19E-09 | 1.093047 | 0.042615 |
| ACVRL1 | -1.50426 | 2.54E-18 | 0.957411 | 0.044483 |
| IGLV5-48 | -2.84863 | 1.67E-15 | 1.144904 | 0.046039 |
| A2M | -1.26394 | 7.65E-17 | 1.008646 | 0.047604 |
| CMKLR1 | -1.43947 | 1.61E-16 | 1.200541 | 0.049798 |
FC: fold change; FDR: false discovery rate; HR: hazard ratio.