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. 2020 Apr 8;12(7):6049–6057. doi: 10.18632/aging.103000

Table 2. Results of meta-analysis and subgroup analysis.

No. of studies OR(95%CI) P-Value Heterogeneity Model used
Ph
Hypertension 6 2.29(1.69-3.10) <0.001 4.0% 0.391 Fixed
 ICU care 2 2.97(0.70-12.55) <0.001 55.7% 0.133 Romdon
 Clinical symptoms 4 2.03(1.45-2.85) <0.001 0 0.947 Fixed
Diabetes 6 2.47(1.67-3.66) <0.001 39.3% 0.144 Fixed
 ICU care 2 1.24(0.07-22.98) 0.883 82.0% 0.018 Romdon
 Clinical symptoms 4 2.66(1.73-4.10) <0.001 0 0.429 Fixed
COPD 6 5.97(2.49-14.29) <0.001 0 0.995 Fixed
 ICU care 2 8.30(1.26-54.43) 0.027 0 0.885 Fixed
 Clinical symptoms 4 5.37(1.99-14.46) 0.001 0 0.973 Fixed
Liver disease 5 0.67(0.30-1.49) 0.326 0 0.573 Fixed
 ICU care 2 0.41(0.05-3.53) 0.713 0 0.416 Fixed
 Clinical symptoms 3 0.74(0.31-1.75) 0.492 16.9% 0.300 Fixed
Malignancy 4 2.29(1.00-5.23) 0.049 0 0.627 Fixed
 ICU care 2 1.67(0.49-5.61) 0.410 0 0.547 Fixed
 Clinical symptoms 2 3.18(1.05-9.64) 0.041 0 0.370 Fixed
Renal disease 4 2.51(0.93-6.78) 0.070 0 0.501 Fixed
 ICU care 1 2.94(0.40-21.69) 0.290 - - -
 Clinical symptoms 3 2.38(0.76-7.50) 0.237 15.0% 0.308 Fixed
Cardiovascular disease 4 2.93(1.73-4.96) <0.001 0 0.989 Fixed
 ICU care 2 2.69(1.14-6.34) 0.023 0 0.924 Fixed
 Clinical symptoms 2 3.10(1.59-6.02) 0.001 0 0.834 Fixed
Cerebrovascular disease 3 3.89(1.64-9.22) 0.002 44.8% 0.163 Fixed
 ICU care 1 20.20(2.34-174.44) 0.006 - - -
 Clinical symptoms 2 2.07(0.70-6.12) 0.189 0 0.852 Fixed