Table 2. The relationship between ACEI/ARB and CIAKI before and after matching all patients.
Definitions | Unmatched cohort | Matched cohort | ||
OR (95% CI)* | P value* | OR (95% CI)** | P value** | |
Primary CIAKI end point: | ||||
SCr increase ≥ 25% or 44 umol/l in 72 hours | 1.757 (1.401-2.203) | <0.001 | 1.993 (1.415-2.809) | <0.001 |
Other defining criteria for CIAKI: | ||||
SCr increase ≥ 25% or 44 umol/l in 24 or 48 hours | 1.583 (1.259-1.990) | <0.001 | 1.725 (1.209-2.460) | <0.001 |
SCr increase ≥ 50% or 26.4 umol/l in 48 hours | 2.009 (1.510-2.673) | <0.001 | 2.695 (1.672-4.343) | <0.001 |
*Multivariable analysis was applied in the unmatched cohort. OR and 95% confidence interval (CI) were obtained by adjusting variables.
**Conditional logistic model was applied in the matched cohort, OR with 95% confidence interval (CI) was obtained.
Abbreviations: SCr, serum creatinine; CIAKI, contrast-induced acute kidney injury.