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. 2020 Apr 2;19(6):3657–3663. doi: 10.3892/etm.2020.8640

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Copyright: © Lv et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of co-culture of ASCs and BMSCs on the TGF-β/Smads pathway. (A) Expression of TGF-β1, Smad2 and p-Smad2 detected via WB after BMSCs and ASCs were co-cultured for 3 and 7 days. (B) Relative quantitative expression histograms of TGF-β1, Smad2 and p-Smad2. Co-culture with BMSCs remarkably reduces the expression of TGF-β1, Smad2 and p-Smad2 in ASCs (P<0.05). ^*P<0.05, there is an obvious difference between ASCs + BMSCs group and ASCs group. ASCs, astrocyte-spinal cords; BMSCs, bone marrow mesenchymal stem cells; TGF-β1, transforming growth factor-β.