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. 2020 Apr 2;19(6):3657–3663. doi: 10.3892/etm.2020.8640

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Copyright: © Lv et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Influence of the transplantation of BMSCs on the TGF-β/Smads pathway at the spinal injury site of rats. (A) After 1 week, the expression of TGF-β1, Smad2 and p-Smad2 in each group is remarkably upregulated in SCI group compared with those in Sham group (P<0.05), and injection of BMSCs can downregulate the above expression (P<0.05). (B) After 3 weeks, the expression of TGF-β1, Smad2 and p-Smad2 in each group exhibits no notable differences among groups (P>0.05). ^*P<0.05, there are significant differences between the groups (P<0.05). BMSCs, bone marrow mesenchymal stem cells; TGF-β1, transforming growth factor-β.