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. 2020 Apr 21;9(1):1748981. doi: 10.1080/2162402X.2020.1748981

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Intracellular cytokine expression in peripheral blood mononuclear cell (PBMC) derived CD4⁺ T cells after re-stimulation with purified protein derivative (PPD). Patient-derived CD4⁺ T cells from PBMCs before (I1 = instillation 1), and during the course of the induction phase (I3, I6) were assessed for the indicated intracellular cytokine concentrations. The colored lines depict the individual development per patient. Fold-changes compared to the pre-treatment status (I1) of the percentage of CD4⁺ T cells producing the cytokine of interest are shown.